Integrated Healthrisk: Predicting Cardiovascular Events in Cancer Patients

DOI : 10.17577/IJERTV13IS050036.

Download Full-Text PDF Cite this Publication

Text Only Version

Integrated Healthrisk: Predicting Cardiovascular Events in Cancer Patients

Parimal Patil Department Of Computer Engineering Dr.D.Y.Patil Institute Of Technology

Pimpri, Pune, India

Sanket Patil Department Of Computer Engineering Dr.D.Y.Patil Institute Of Technology

Pimpri, Pune, India

Lalit Patel

Department Of Computer Engineering Dr.D.Y.Patil Institute Of Technology Pimpri, Pune, India

Mitali Doshi Department Of Computer Engineering Dr.D.Y.Patil Institute Of Technology

Pimpri, Pune, India

AbstractThe final-year project, entitled Integrated Health Risk: Predicting Cardiovascular Events in Cancer Patients with Machine Learning, aims to address the intricate relationship between cancer and cardi-ovascular health. Its primary objective is to identify individuals at risk early on by developing a predictive model using advanced ma-chine learning techniques, all while emphasizing ethical considera-tions in data handling. The methodology involves a comprehensive approach to gathering and preprocessing clinical data. Ensemble models and feature se- lection techniques are utilized to ensure opti-mal prediction accu- racy. Throughout the project, transparency and interpretability remain paramount, aligning with ethical standards and ensuring that healthcare professionals can easily understand the models decisions. The potential impact of this project is significant, offering the possibility of timely interventions and improved patient care. By providing healthcare professionals with an accu-


    In todays fast-paced world, many individuals prioritize wealth and fame over their health, often neglecting crucial aspects such as diet and lifestyle. This ne-glect frequently results in health issues like high blood pressure, diabetes, and other ailments at relatively young ages. These factors significantly contribute to the development of heart diseases, which pose a serious threat due to the hearts pivotal role in the bodys functioning.

    Diagnosing heart diseases is challenging, given their com- plex nature. Hence, the development of automated prediction systems to assess a patients heart condi-tion is imperativefor more effective treatment. The heart serves as the core organ in the circulatory system, responsible for pumping blood throughout the bodys vessels. This circulatory system is vital for distributing blood, oxygen, and other essential nutrients to various organs, underscoring the critical importance of maintaining heart health for overall well-being.

    In essence, the demands and lifestyle choices prevalent in modern society elevate the risk of heart diseases. To confront this issue, it is crucial to develop automat-ed heart disease prediction systems. Such systems not only enhance patient carebut also alleviate the burdens faced by medical professionals and patients alike.

    Asst.Prof Sharad Adusre

    Project Guide Department Of Computer Engineering Dr.D.Y.Patil Institute Of Technology

    Pimpri, Pune, India

    rate and in-terpretable predictive model, the project empowers them to make informed decisions. Moreover, it contributes to a deeper under-standing of the complex interplay between cancer and cardiovascu-lar health, fostering further exploration and innovation in the field. As the project concludes, its results have the potential to transform healthcare practices. By integrating the predictive model into clini-cal settings, it could reduce costs and save lives. In summary, this project represents a crucial step forward in addressing a pressing healthcare challenge, benefiting patients and the medical communi-ty, while advancing our com- prehension of the dynamics between cancer and cardiovascular health.

    Index Terms: Heart Diseases; Cardiovascular; Machine Learning; KNN Classifi-er; Logistic Regression; Decision Tree; Random Forest; Na¨ve Bayes, ANN.


    The literature review encompasses three studies focusing on the development of heart disease prediction systems using datamining and machine learning techniques.

    In the first study conducted by Devendra Ratnaparkhi, Tushar Mahajan, and Vishal Jadhav in November 2015, seven classifiers were employed to predict heart disease. The deci- sion tree classifier (DTC) achieved the highest accuracy of 73.12

    The second study by V. Krishnaiah, Dr. G. Narsimha, and Dr.

    N. Subhash Chandra in December 2013 explored heart disease prediction using CRISPADM and decision trees. The results indicated a satisfactory accuracy standard, particularly when utilizing Random Forest classification to predict heart disease without the need for specialized equipment. Never- theless, the prediction results were not consistently accurate, and the data mining techniques struggled to facilitate effective decision-making, especially with large datasets

    In April 2022, Rahul Vashistha, Aditya Randive, Pallavi Gade, and Gaurav Pardeshi conducted a study focusing on heart disease prediction using machine learning algorithms and website implementation. By employing two different algorithms, they achieved an accuracy of 93 Overall, while these studies highlight the potential of data mining and machine learning techniques in predicting heart disease, they also underscore the challenges and limitations associated with model accuracy, dataset size, and computa- tional complexity.


    Proposed Methodology for Heart Disease Prediction System Using Data Mining and Machine Learning Techniques:

    1. Data Acquisition and Preprocessing:

      The initial step involves collecting a diverse dataset encom- passing various attributes relevant to heart disease, including demographic information, medical history, and clinical mea- surements such as cholesterol levels and blood pressure. This dataset undergoes meticulous preprocessing to address issues such as missing values, outliers, and data inconsistencies. Cleaning and standardization techniques are employed to ensure data quality and consistency across all attributes.

    2. Feature Engineering and Selection:

      Feature engineering techniques are applied to extract infor- mative features from the dataset that have a significant impact on predicting heart disease. This may involve transforming or combining existing features to create new ones that capture important patterns or relationships in the data. Subsequently, feature selection methods are utilized to identify the most rel- evant subset of features that contribute to accurate prediction models, thereby reducing dimensionality and computational complexity.

    3. Algorithm Selection and Training:

      A comprehensive range of data mining and machine learn- ing algorithms is explored, including decision trees, random forests, support vector machines, and logistic regression. These algorithms are trained on the preprocessed dataset to build predictive models for heart disease. Various model evaluation metrics such as accuracy, precision, recall, and F1-score are used to assess the performance of each algorithm and identify the most promising candidates for further refinement.

    4. Cross-Validation and Model Evaluation:

      To assess the robustness and generalization ability of the trained models, the dataset is partitioned into multiple folds. Each model undergoes training and evaluation on distinct subsets of the data. This approach ensures thorough exami- nation of model performance across diverse samples,thereby enhancing confidence in the models capacity to generalize well to unseen data. This process helps to mitigate overfitting and offers a more precise assessment of model performance.

      Additionally, model evaluation is conducted using validation datasets to validate the effectiveness of the trained models in real-world scenarios.

    5. Hyperparameter Tuning and Optimization:

      Hyperparameter optimization methods like grid search and random search are utilized to fine-tune the parameters of the selected algorithms. This iterative process involves system- atically exploring different combinations of hyperparameters to optimize model performance. The goal is to identify the optimal set of hyperparameters that maximizes the predictive accuracy of the models.

    6. Ensemble Learning and Model Fusion:

      Ensemble learning techniques such as bagging, boosting, and stacking are investigated to combine multiple base models and improve prediction accuracy. The variety of individual models enhances their performance compared to any single model, as it capitalizes on their diverse strengths and charac- teristics. By aggregating the predictions of multiple models, ensemble learning enhances the robustness and stability of thepredictive system.

    7. Implementation and Deployment:

      The developed predictive models are implemented intoa user-friendly web-based application or software tool for practical use. The application interface is crafted to facilitate efficient usage and navigation, easy access and interpretation of the model predictions by healthcare professionals and patients. Additionally, deployment strategies are employed to ensure seamless integration with existing healthcare systems and workflows.

    8. Continuous Monitoring and Maintenance:

      Continuous monitoring of the deployed models is essential to track their performance over time and detect any potential drift or degradation in predictive accuracy. Regular updates and retraining of the models are conducted using new datato adapt to evolving healthcare trends and ensure optimal performance. Furthermore, robust quality assurance protocols are implemented to address any issues or challenges that may arise during operation.

    9. Ethical Considerations and Regulatory Compliance: Adherence to ethical guidelines and regulatory stan- dards concerning patient data privacy and confidentiality is paramount throughout the entire development and deploymentprocess. Measures such as data anonymization, encryption, and access control are implemented to safeguard sensitive information and ensure compliance with relevant regulations such as the Health Insurance Portability and Accountability Act (HIPAA).

      By following this comprehensive methodology, researchers can develop a highly effective heart disease prediction system that leverages the power of data mining and machine learning techniques to improve patient outcomes and advance medical research in the field of cardiovascular health.


      1. ML Results

        Fig. 1. Results comparing various models with our model

        Fig. 2. Results given by our own model

      2. Web Page

    Fig. 3. Home Page


    Fig. 4. Entering Details

    Fig. 5. Final Result


    In summary, the proposed methodology for developing a heart disease prediction system using data mining and machine learning techniques offers substantial promise for enhancing patient outcomes and driving advancements in cardiovascular health research. By following this methodology, researchers can effectively harness diverse datasets and advanced algo- rithms to construct precise predictive models for identifying individuals at risk of heart disease.

    The results obtained from implementing this methodology showcase encouraging performance metrics, including high accuracy and robustness across various machine learning algorithms. Additionally, feature selection and engineering methods contribute to the interpretability of the models by pinpointing the most relevant predictors of heart disease. Furthermore, ensemble learning techniques bolster prediction accuracy by amalgamating the strengths of multiple base models.

    The prototype heart disease prediction system, characterized by a user-friendly interface accessible to both healthcare pro- fessionals and patients, facilitates early detection and personal- ized treatment strategies. Continuous monitoring and updates ensure the ongoing reliability and efficacy of the predictive models, while strict adherence to ethical and regulatory stan- dards upholds patient privacy and confidentiality.

    Ultimately, the development and deployment of a heart disease prediction system represent a pivotal advancement in preventive healthcare, enabling proactive interventions and tai- lored treatment plans to alleviate the burden of cardiovascular disease and enhance patient outcomes. Ongoing research and innovation in this domain hold the potential to refine and

    optimize predictive models further, thereby driving


  1. Heart Disease Prediction System Using Data Mining Technique by Devendra Ratnaparkhi, Tushar Mahajan, ,Vishal Jadhav (Inter- national Research Journal of Engineering and Technology (IRJET)

  2. Heart Disease Prediction System Using CRISPADM and Decision Trees by V.Krishnaiap ,Dr.G.Narsimha , Dr.N.Subhash Chandra (CVR Jour-nal of Science and Technolo- gy)

  3. Machine Learning-Based Model to Predict Heart Disease in Early Stage Employing Different Feature Selection Techniques by awsar Ahmed,

    Francis M. Bui,Fahad Ahmed Al-Zahrani, and Mohammad Ali Moni

  4. (Hindavi Biomed Research International)

  5. .Suma V, R Amog Shetty, Rishab F Tated, Sunku Rohan, Triveni S Pujar, a CCNN based Leaf Disease Identification and Remedy Recommen- dation Systema C, Proceedings of the Third International Conference on Electronics Communication and Aerospace Technology [ICECA 2019], (12- 14June,2019)

  6. Lu, J., Tan, L., Jiang, H. (2021). Review on Convolutional Neural Net- work (CNN) Applied to Plant Leaf Disease Classification. Agriculture, 11(8), 707. doi:10.3390/agriculture11080707

  7. Monigari, Vaishnavi. (2021). Plant Leaf Disease Prediction. International Journal for Research in Applied Science and Engineering Technology. 9. 1295-1305. 10.22214/ijraset.2021.36582.

  8. Sujatha, R., Chatterjee, J. M., Jhanjhi, N., Brohi, S. N. (2021). Performance of deep learning vs machine learning in plant leaf disease detection. Microprocessors and Microsystems, 80, 103615.